ARE YOU HAVING A CHALLENGE GETTING WEIGHT LOSS MEDICATIONS?

At Wound Solution, we believe in setting the pace and staying ahead of the curve. Our partnered company, Pure Rx, specializes in pharmaceutical distribution, including weight loss peptides and other specialties. Pure Rx has invested time, money, and effort into developing an online system for processing pharmaceutical orders for cash-paying customers.

We have effectively solved the industry challenges of weight loss peptides orders:

  1. Distributors, pharmacies, and clinics no longer need to pay large amounts upfront for inventory. Solution: Products will be shipped directly to the patients.

  2. Expensive refrigerated storage is no longer an issue. Solution: We will be shipping directly to patients.

  3. Increased profit margins for our partners. Solution: Pure RX will handle inventory management and logistics for distributors, pharmacies, and clinics.

    This is an ideal solution for cash-paying customers using weight loss peptides. Stay tuned—we look forward to streamlining your order processing and helping you succeed. If you have any questions or need further information, please feel free to ask!

WEIGHT LOSS: TIRZEPATIDE VS. SEMAGLUTIDE

How are each sold?

Semaglutide:

Sold under the brand names Ozempic (FDA Approved 2017), Wegovy (FDA Approved 2021), & Rybelsus (FDA Approved 2019). Also sold as generic biologics with NDCs as Semaglutide blends.

Tirzepatide:

Sold under the brand name Mounjaro (FDA Approved 2022). Also sold as generic biologics with NDCs as Tirzepatide blends.

Summary of Both Products:

Approved by the FDA, both are anti-diabetic medications used for the  treatment of type 2 diabetes & as anti-obesity medications for long-term weight management & with all weight-loss strategies, it does require sustained lifestyle changes in order to continue your  success. 

These are perfect weight loss medications for people who are  overweight and obese, with or without diabetes. These medications will simply help you lose weight on the scale along with significant fat loss  reduction. 

Semaglutide

Semaglutide is a medication that has been used to treat diabetes since 2019. It works by mimicking the hormone glucagon-like peptide-1 receptor agonist  (GLP-1), which helps the body regulate blood sugar levels. It also  reduces hunger, regulates appetite, & increases feelings of satiety, making it easier to reduce calorie intake. In addition, Semaglutide has been shown to reduce cholesterol levels, triglycerides, as well as overall mortality rates in people with type 2 diabetes. This medication will simply help you lose weight on the scale & is indicated for the treatment of overweight & obesity.

What else does it do?

Brain

  • Increases synaptic transmission, nerve protection, memory, neuronal stem cell proliferation, motor function, & satiety

  • Decreases neuroinflammation

CVD (cardiovascular disease)

  • Increases CVD protection, heart rate, and anti-inflammatory actions

  • Improves endothelial function, myocardial ischemia, lipids

Liver

  • Decreased glucose production, liver fat content, liver enzymes, & hepatic steatosis

Pancreas

  • Increases insulin secretion

  • Increases & protects pancreatic β cells

Gut

  • Decreased gastric emptying & peristalsis, thus increasing nutrient absorption & normalizing PPG (postprandial glucose) elevations.

Note: It is important to have a healthy gut for optimal nutrient absorption & hormone balance

Tirzepatide

Tirzepatide is a medication that was recently approved for use in adults with type 2  diabetes. It is a dual glucose-dependent insulinotropic polypeptide  (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist (RA). This means it works by imitating not one but two unique incretin hormones produced by the human body. It works by stimulating GLP-1 production in  the body, which helps the body produce more insulin when needed. GIP has been shown to decrease food intake & increase energy expenditure, therefore resulting in weight reductions & when combined with GLP-1 receptor agonism, may result in greater effects on markers of metabolic dysregulation such as body weight, glucose, & lipids. Additionally,  Tirzepatide has been found to lower fasting blood glucose levels &  increase weight loss in participants who were overweight or obese at the start of clinical trials. This suggests that it may benefit those looking to shed excess pounds quickly & safely. This medication has all the benefits of Semaglutide for weight loss with appetite suppression, but it also adds the component of fat loss; in other words, you’ll lose weight & keep it off for the long haul.

What else does it do:

  • Stimulate pancreatic β cells insulin release.

  • Note: in DM (diabetes mellitus) patients, GIP secretion is reduced; however, it can be restored by improving glycemic control.

  • GIP: Protects against hypoglycemia; improves TG  (triglyceride) clearance; improves adipose insulin sensitivity, which may prevent ectopic fat deposition.

Who should not or should to be cautious about taking these medications:

  • Shouldn’t: Those with a personal or family history of thyroid cancer; multiple endocrine neoplasia syndrome type 2; other DM  medications, especially insulin & sulfonylureas; history of pancreatitis, history of gall bladder disease; kidney disease; tachycardia; retinopathy; pregnant, breast-feeding, or trying to get pregnant.

  • Caution: Metformin; those with an elevated HR, as there are GLP-1 receptors in the SA Node (sinoatrial node); GI disorders; those with HTN (high blood pressure-hypertension) on BP (blood pressure) medications.

    • Decreased glucose production, liver fat content, liver enzymes, & hepatic steatosis.

Additional Benefits:

  • Reduced inflammation: Both medications are proven to reduce inflammation markers, leading to decreased inflammation response & oxidative stress.

  • Regulates digestion: This regulation is directly tied to how quickly food moves from the stomach to the intestines. Overall, this will leave you feeling fuller longer & help control the sugar absorption in the intestines.

  • Improved metabolic function: These medications regulate blood sugar levels by increasing insulin and decreasing glucagon only when the blood sugar levels are high. They also improve whole-body energy metabolism by increasing the insulin sensitivity of muscle cells and regulating fat cell development. Even if you are not severely overweight, you can’t go wrong with improving your metabolic profile!

  • BPC-157: This peptide is added to both medications and acts systematically in the digestive tract to combat leaky gut, IBS, and gastro-intestinal cramps. It helps maintain the integrity of the mucosal lining of the GI tract, improve digestive function, improve gut-related issues, and reduce the side effects of the medications.

  • Other: May reduce the likelihood of cardiovascular events such as heart attack, stroke, or death in adults with type 2 diabetes and known heart disease. Helps release insulin and lowers the amount of glucose produced by the liver when glucose rises at mealtime.  Also slows the absorption of mealtime glucose.

We offer both Name Brand and Generic Pharmaceuticals

What's the difference?

Did you know that prescription drug prices in the U.S. are an average of 2.5 times higher than in other Western countries? With this in mind, you might be wondering if switching to a generic drug is right for you. Let’s look at the differences between the generic and brand-name versions of prescription drugs. 

What are generic drugs?

A generic drug is a medication with the exact same active ingredient as the brand-name drug. It is taken the same way and offers the same effect. Generic drugs do not need to contain the same inactive ingredients as the name-brand product, and they can only be sold after the brand-name drug’s patent expires. 

Is there a difference between generic and brand-name drugs?

There are only two main differences between generic and brand-name drugs: 

  1. The inactive ingredients, such as flavoring or preservatives, may change 

  2. Generics generally cost less than brand-name versions

How are generic and brand-name drugs similar?

The U.S. Food and Drug Administration sets standards for generic drugs to ensure they work the same way and have the same benefits and risks as their brand-name counterparts.

Generic drugs must match the brand-name versions in the following ways :

  • They must have the same active ingredients 

  • The dosage and strength must be identical 

  • The overall quality, stability, and safety must be the same     

A generic drug must be “bioequivalent” to the brand-name product, meaning they must be chemically similar. A recent study that compared generics to brand-name drugs found, on average, only a 3.5% difference in absorption into the body.

Are generic drugs made with the same standards as brand-name drugs?

Yes. The FDA requires a generic drug manufacturer to follow the same standards as the brand-name manufacturing process. Generic drugs are often made in the same facilities. The agency conducts on-site inspections each year to ensure the manufacturers follow the rules. 

What are the potential cost savings of using generic drugs?

Generic medications, on average, are 80–85% less expensive than brand-name medications. 

Always talk to your doctor about the best course of your treatment. Some medicines don't have a generic version, but your doctor or pharmacist can see if there are alternatives you can try. You may find the savings are well worth the change.

How else can I save money on prescription drug costs?

Besides switching to a generic, here are a few ways you may be able to cut costs on your prescription: 

  • Ask for a 90-day supply at your pharmacy: This may help lower your copay, which may add up to significant savings.

  • Try mail-order: Check with your insurance policy to see if you have a lower copayment if you get your prescription through the mail.    

  • Pick a pharmacy in your plan’s preferred network: Make sure the pharmacy you visit is in your plan’s network before getting a refill.    

  • Sign up for a prescription discount program: These programs work directly with drug manufacturers to help keep costs down for patients.    

  • Search for non-profit organizations to help lower costs: These organizations may help you find assistance programs to lower the cost of your prescription.    

  • Pharmaceutical companies can help: Some companies sponsor assistance programs to help cover prescription  costs for low-income individuals or people with disabilities. 

Navigating the price of prescription drugs can be challenging, but remember: 

  • Never cut pills.

  • Never skip a dose.

  • Never stop taking your medication without speaking with your Doctor first.